New research on mesothelioma prognosis


Further evidence of the global nature of this cancer this week, firstly , new research under way in Korea suggest they are going to see an increasing number of cases over the next 30 years. The a neew study from one of the country’s leading cancer centers suggests that the nuclei of mesothelioma cells may hold vital clues for predicting patient survival.

Though as an individual not sure you would want to know, but anything that suggest they are learning more about Mr Nasty has to be good.Epithelioid mesothelioma is the most common subtype.  Doctors often use the cancer’s stage – a measure of cancer extent and severity – to predict how well patients will respond to treatment.  But now a group of scientific researchers from Memorial Sloan-Kettering Cancer Center in the U.S. and Kagawa University in Japan believe they have found an even more effective prognostic indicator – inside the nucleus of mesothelioma cells.

To conduct their experiment, the researchers examined the slides of 232 patients who had been diagnosed with the epithelioid type of malignant pleural mesothelioma. They then examined the nuclei of the cell samples to evaluate them on seven different features.

Thorough analysis of each mesothelioma cell sample revealed that two of the features, nuclear atypia and mitotic count, were directly related to patient prognosis. 

“Not only was nuclear grade an independent predictor of overall survival, but it was also a stronger discriminator of survival than all currently available factors,”

Good to see that the research into this is going on all over the world



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